Lipid M Datasheet DC Chemicals

Description	Lipid M is an ionizable lipid used to form lipid nanoparticles for delivering RNA. LNPs formulated with Lipid M delivered luciferase mRNA in mice resulting in higher protein expression compared to the benchmark lipid DLin-MC3-DMA. Lipid M LNPs delivering IgG mRNA showed prolonged expression compared to MC3 in non-human primates after intramuscular injection. LNPs formulated with Lipid M were able deliver EGFP and ciliary neurotrophic factor (CNTF) mRNA to retinal pigment epithelium (RPE) cells after intravitreal injection. Acute inflammation was not observed up to 6 hours post injection.
Cat.No	DC67242
Name	Lipid M

Chemical Properties

CAS
Formula	C44H87NO5
MW	710.18
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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