Montanide 50 is a water-in-oil (W/O) emulsion-based vaccine adjuvant developed by SEPPIC. It forms a stable oil-phase microenvironment that prolongs antigen retention at the injection site, enhancing antigen immunogenicity and inducing potent immune responses. Montanide ISA 50V is particularly suitable for vaccines requiring robust cellular and humoral immunity, such as cancer vaccines and therapeutic vaccines.
This adjuvant is characterized by its high immune-enhancing capacity, excellent stability, and compatibility with various antigens. Montanide ISA 50V has demonstrated significant efficacy in cancer vaccine development, effectively activating antigen-specific T cell responses and promoting anti-tumor immunity. Additionally, it has been utilized in research for vaccines against infectious diseases, such as HIV and malaria.
In summary, Montanide ISA 50V, as an efficient water-in-oil adjuvant, provides critical technical support for the development of therapeutic and cancer vaccines through its unique sustained-release mechanism and immune-enhancing properties. It is particularly effective in scenarios requiring strong cellular immune responses.
Cat.No
DC67255
Name
Montanide 50
Chemical Properties
CAS
Formula
MW
Storage
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
References
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