KT-333 ammonium Datasheet DC Chemicals

Description	KT-333 ammonium (Compound A) is a targeted molecular glue degrader that induces STAT3 protein degradation via the ubiquitin-proteasome pathway. The compound facilitates this process by simultaneously engaging both STAT3 and the VHL E3 ubiquitin ligase, demonstrating remarkable degradation selectivity. With potent antitumor efficacy, KT-333 ammonium shows particular promise for investigating therapeutic interventions in hematologic malignancies, including large granular lymphocytic leukemia (LGL-L), peripheral T-cell lymphoma (PTCL), and cutaneous T-cell lymphoma (CTCL).
Cat.No	DC67366
Name	KT-333 ammonium

Chemical Properties

CAS	2839758-34-6
Formula	C60H77CLN11O14PS
MW	1274.81
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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