ChREBPα/14-3-3 regulator-1 Datasheet DC Chemicals

Description	ChREBPα/14-3-3 regulator-1 (Compound 43) is a selective molecular glue that stabilizes the ChREBP/14-3-3 protein complex with an EC50 of 3.8 μM. By enhancing this interaction, the compound demonstrates cytoprotective effects against glucolipotoxicity in pancreatic β cells while preserving cellular function. These properties position it as a promising investigational tool for type 2 diabetes research.
Cat.No	DC67371
Name	ChREBPα/14-3-3 regulator-1

Chemical Properties

CAS
Formula	C16H15F3NO5P
MW	389.26
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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