BRD4 degrader-2 Datasheet DC Chemicals

Description	BRD4 degrader-2 (Compound JP-2-197) is a covalent monovalent molecular glue that orchestrates targeted BRD4 degradation through ternary complex formation with the E3 ligase RNF126. This compound selectively engages both BRD4 isoforms (long and short) for proteasomal elimination, demonstrating pan-isoform degradation capability in cellular systems.
Cat.No	DC67373
Name	BRD4 degrader-2

Chemical Properties

CAS	3036530-43-2
Formula	C34H33CLN6O4S
MW	657.18
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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