IKZF3 degrader 1 Datasheet DC Chemicals

Description	IKZF3 degrader 1 (compound 19a) is a potent molecular glue that induces targeted IKZF3 degradation (EC50 = 12 nM) by facilitating its recruitment to the cereblon (CRBN) E3 ubiquitin ligase complex. This enforced protein-protein interaction triggers subsequent ubiquitination and proteasomal elimination of IKZF3.
Cat.No	DC67375
Name	IKZF3 degrader 1

Chemical Properties

CAS
Formula	C25H18BRCL3N2O5
MW	612.68
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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