STING Degrader-1 Datasheet DC Chemicals

Description	STING Degrader-1 (compound 2) is a covalent molecular glue that simultaneously engages STING and its cognate E3 ligase, inducing targeted protein degradation. The compound exhibits a characteristic hook effect, achieving maximal STING depletion (75%) at 10 μM, while higher concentrations (30 μM) show reduced degradation efficiency (~30%).
Cat.No	DC67379
Name	STING Degrader-1

Chemical Properties

CAS
Formula	C26H24N4O7
MW	504.49
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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