WIZ degrader 8 Datasheet DC Chemicals

Description	WIZ degrader 8 (compound 10) is a potent and selective molecular glue that induces targeted degradation of the transcription factor WIZ, resulting in robust upregulation of fetal hemoglobin (HbF) expression. This dual activity—WIZ depletion coupled with HbF induction—positions it as a promising therapeutic candidate for sickle cell disease.
Cat.No	DC67391
Name	WIZ degrader 8

Chemical Properties

CAS	2879251-26-8
Formula	C21H27N3O4
MW	385.46
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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