KRAS ligand 4 Datasheet DC Chemicals
Description KRAS ligand 4 (compound 2) is a SOS1-targeting bifunctional molecular glue that suppresses oncogenic signaling by degrading key KRAS pathway components, evidenced by reduced pERK and pS6 levels. It demonstrates broad-spectrum activity against diverse KRAS mutations, disrupting proliferation across resistant cancer models.
Cat.No DC67403
Name KRAS ligand 4

Chemical Properties

CAS
Formula C24H28CLF3N6O3
MW 540.97
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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