XNW34017 Datasheet DC Chemicals
Description XNW34017 is a PROTAC targeting Aurora A. It binds both Aurora A and the E3 ligase CRBN, leading to ubiquitination of Aurora A by CRBN, followed by specific degradation via the ubiquitin-proteasome system (UPS). This results in cell cycle arrest and apoptosis, thereby killing tumor cells.
Cat.No DC68065
Name XNW34017

Chemical Properties

CAS
Formula
MW
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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