UR778Br Datasheet DC Chemicals

Description	UR778Br is a small-molecule inhibitor targeting the GTPase-activating protein–related (GRD) domain of IQGAP1, with demonstrated anti-leukemia activity in both in vitro and in vivo preclinical models. In human AML cell lines (e.g., MOLM13, MV4-11, THP-1, U937) and primary AML blasts, UR778Br shows dose-dependent suppression of proliferation (effective low-µM range), induces G2/M cell-cycle arrest, and triggers apoptosis.
Cat.No	DC68174
Name	UR778Br

Chemical Properties

CAS	866127-80-2
Formula	C20H20BRNO4
MW	418.29
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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