DFHO Datasheet DC Chemicals

Description	DFHO is a fluorogenic ligand of Corn fluorogenic aptamer. The RNA aptamer, Corn binds DFHO with a Kd value of 70 nM and converts it to a fluorescent form, enabling RNA imaging in cells.
Cat.No	DC36886
Name	DFHO

Chemical Properties

CAS	1420815-34-4
Formula	C12H9F2N3O3
MW	281.214969396591
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

[1]. Wenjiao Song, et al. Imaging RNA polymerase III transcription using a photostable RNA-fluorophore complex. Nat Chem Biol. 2017 Nov;13(11):1187-1194. [2]. Hyaeyeong Kim, et al. A Fluorogenic RNA-Based Sensor Activated by Metabolite-Induced RNA Dimerization. Cell Chem Biol. 2019 Dec 19;26(12):1725-1731.e6.

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