D-3263 HCl Datasheet DC Chemicals
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Cat.No DC9850
Name D-3263 HCl

Chemical Properties

CAS 1008763-54-9
Formula C21H31N3O3
MW 373.4891
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological activity

Description CAS NO.：1008763-54-9
Product Name：3-(2-Aminoethyl)-1-((1R,2S,5R)-2-isopropyl-5-methylcyclohexanecarbonyl)-5-methoxy-1H-benzo[d]imidazol-2(3H)-one
Synonyms：D-3263 (hydrochloride);D3263 hydrochloride;3-(2-aminoethyl)-1-((1R,2S,5R)-2-isopropyl-5-methylcyclohexanecarbonyl)-5-methoxy-1H-benzo[d]imidazol-2(3H)-one;3-(2-aminoethyl)-1-((1R,2S,5R)-2-isopropyl-5-methylcyclohexane-1-carbonyl)-5-methoxy-1,3-dihydro-2H-benzo[d]imidazol-2-one;70FBL3TX3E;SB17275;2H-Benzimidazol-2-one, 3-(2-aminoethyl)-1,3-dihydro-5-methoxy-1-(((;D-3263 hydrochloride
EINEC:
Molecular Formula：C21H31N3O3
Molecular Weight：373.4891
Target:
In Vivo
In Vitro D-3263 hydrochloride binds to and activates TRPM8, which may result in an increase in calcium and sodium entry; the disruption of calcium and sodium homeostasis; and the induction of cell death in TRPM8-expressing tumor cells. D-3263 hydrochloride may decrease dihydrotestosterone (DHT) levels, which may contribute to its inhibitory effects on prostate cancer and BPH[1].
Kinase Assay
Cell Assay
Animal Administration

References

[1]. enteric-coated TRPM8 agonist D-3263 hydrochloride
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