Defactinib hydrochloride Datasheet DC Chemicals
Description Defactinib is a potent, selective, and orally active FAK inhibitor with demonstrated tolerability and preliminary clinical activity working as a single agent as well as in combination with paclitaxel.
Cat.No DC10100
Name Defactinib hydrochloride

Chemical Properties

CAS 1073160-26-5
Formula C20H22CLF3N8O3S
MW 546.9537
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

[1]. Kang Y, et al. Role of focal adhesion kinase in regulating YB-1-mediated paclitaxel resistance in ovarian cancer. J Natl Cancer Inst. 2013 Oct 2;105(19):1485-95.
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