EGFR-IN-11 Datasheet DC Chemicals
Description EGFR-IN-11 is a fourth-generation EGFR-tyrosine kinase inhibitor (EGFR-TKI) with an IC50 of 18 nM for triple mutant EGFRL858R/T790M/C797S. EGFR-IN-11 significantly suppresses the EGFR phosphorylation, induce the apoptosis, and arrest cell cycle at G0/G1.
Cat.No DC28681
Name EGFR-IN-11

Chemical Properties

CAS
Formula C29N9O2SH35
MW 573.7123
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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