EGFR-IN-1 TFA Datasheet DC Chemicals
Description EGFR-IN-1 TFA is an orally active and irreversible L858R/T790M mutant selective EGFR inhibitor. EGFR-IN-1 TFA potently inhibits Gefitinib-resistant EGFR L858R, T790M with 100-fold selectivity over wild-type EGFR. EGFR-IN-1 TFA displays strong antiproliferative activity against the H1975 cells and the first line mutant HCC827 cells. Antitumor activity.
Cat.No DC41127
Name EGFR-IN-1 TFA

Chemical Properties

CAS
Formula C30H31F3N6O6
MW 628.60
Storage Powder-20°C3 years4°C2 yearsIn solvent-80°C6 months-20°C1 month

References

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