CID 138454799 Datasheet DC Chemicals
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Cat.No DC51010
Name CID 138454799

Chemical Properties

CAS 2320561-35-9
Formula C55H65N5O9S2
MW 1004.26271224022
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological activity

Description CAS NO.：2320561-35-9
Product Name：CID 138454799
Synonyms：ERD-308;ERD 308;ERD308;GTPL10565;s8902;compound 32 [PMID: 30990042];(2S,4R)-1-[(2S)-2-[[2-[5-[ethyl-[2-[4-[6-hydroxy-2-(4-hydroxyphenyl)-1-benzothiophene-3-carbonyl]phenoxy]ethyl]amino]pentoxy]acetyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[(1S)-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]ethyl]pyrrolidine-2-carboxamide;CID 138454799
EINECS:
Molecular Formula：C55H65N5O9S2
Molecular Weight：1004.26271224022
Target: DC50: 0.17 nM (ER in MCF-7 cells)[1].
In Vivo
In Vitro
Kinase Assay
Cell Assay
Animal Administration

References

[1]. Hu J, et al. Discovery of ERD-308 as a Highly Potent Proteolysis Targeting Chimera (PROTAC) Degrader of Estrogen Receptor (ER). J Med Chem. 2019 Feb 14;62(3):1420-1442
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