Eculizumab Datasheet DC Chemicals
Description Eculizumab is a long-acting humanized monoclonal antibody targeted against complement C5 and it is used to treat a number of autoimmune conditions.
Cat.No A010
Name Eculizumab

Chemical Properties

CAS 219685-50-4
Synonyms Immunoglobulin,anti-(human complement C5 a-chain) (human-mouse monoclonal 5G1.1 heavy chain), disulfide withhuman-mouse monoclonal 5G1.1 light chain, dimer (9CI);eculizumab;h5G1.1;h5G1.1VHC+h5G1.1VLC;Soliris;Alexion;H5G1.1Vhc H5G1.1vlc;Unii-A3ulp0F556;ECULIZUMABUM
pH value Corresponds to reference standard: PASS
Non-reduced CE-SDS 98.5%
SEC-HPLC 99.7%
Isoelectric Point Corresponds to reference standard:PASS
Bacterial Endotoxins Test <1 EU/ml
Residual Proteins of Host Cell
Exogenous Residual DNA <1 pg/mg
Residual protein A <1 ng/mg
Biological Activity Compared with standard, the range of biological activity is 110%
Osmolality Corresponds to reference standard: PASS
Peptide mapping Corresponds to reference standard: PASS
N-terminal sequence Corresponds to reference standard:PASS

References

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