Description |
Eculizumab is a long-acting humanized monoclonal antibody targeted against complement C5 and it is used to treat a number of autoimmune conditions. |
Cat.No |
A010 |
Name |
Eculizumab |
Chemical Properties
CAS |
219685-50-4 |
|
Synonyms |
Immunoglobulin,anti-(human complement C5 a-chain) (human-mouse monoclonal 5G1.1 heavy chain), disulfide withhuman-mouse monoclonal 5G1.1 light chain, dimer (9CI);eculizumab;h5G1.1;h5G1.1VHC+h5G1.1VLC;Soliris;Alexion;H5G1.1Vhc H5G1.1vlc;Unii-A3ulp0F556;ECULIZUMABUM |
pH value |
Corresponds to reference standard: PASS |
Non-reduced CE-SDS |
98.5% |
SEC-HPLC |
99.7% |
Isoelectric Point |
Corresponds to reference standard:PASS |
Bacterial Endotoxins Test |
<1 EU/ml |
Residual Proteins of Host Cell |
|
Exogenous Residual DNA |
<1 pg/mg |
Residual protein A |
<1 ng/mg |
Biological Activity |
Compared with standard, the range of biological activity is 110% |
Osmolality |
Corresponds to reference standard: PASS |
Peptide mapping |
Corresponds to reference standard: PASS |
N-terminal sequence |
Corresponds to reference standard:PASS |
References
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