Endoxifen (Z-isomer hydrochloride) Datasheet DC Chemicals

Description	Endoxifen HCl, the active metabolite of Tamoxifen, ia a potent and selective estrogen receptor antagonist. Phase 2.
Cat.No	DC8403
Name	Endoxifen (Z-isomer hydrochloride)

Chemical Properties

CAS	1032008-74-4
Formula	C25H27NO2.HCL
MW	409.948
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

[1]. Chae YJ, et al. Endoxifen, the active metabolite of tamoxifen, inhibits cloned hERG potassium channels. Eur J Pharmacol. 2015 Apr 5;752:1-7. [2]. Wu X, et al. Estrogen receptor-beta sensitizes breast cancer cells to the anti-estrogenic actions of endoxifen. Breast Cancer Res. 2011 Mar 10;13(2):R27.

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