Epinastine Datasheet DC Chemicals
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Cat.No DC9467
Name Epinastine

Chemical Properties

CAS 80012-43-7
Formula C16H15N3
MW 249.310403108597
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological activity

Description CAS NO.:80012-43-7
Product Name:Epinastine
Synonyms:Epinastine;3-amino-9,13b-dihydro-1h-dibenz[c,f]imidazo[1,5-a]azepine;Epinastine base;WAL801;3-Amino-9,13b-dihydro-1H-dibenzo[c,f]imidazo[1,5-a]azepine;9,13b-Dihydro-1H-dibenz[c,f]imidazo[1,5-a]azepin-3-amine;Flurinol(R)
EINEC:
Molecular Formula:C16H15N3
Molecular Weight:249.310403108597
Target: Histamine Receptor
In Vivo
In Vitro
Kinase Assay
Cell Assay
Animal Administration

References

[1]. Fugner, A., et al., In vitro and in vivo studies of the non-sedating antihistamine epinastine. Arzneimittelforschung, 1988. 38(10): p. 1446-53. [2]. Roeder, T., J. Degen, and M. Gewecke, Epinastine, a highly specific antagonist of insect neuronal octopamine receptors. Eur J Pharmacol, 1998. 349(2-3): p. 171-7. [3]. Kamei, C., et al., Antiallergic effect of epinastine (WAL 801 CL) on immediate hypersensitivity reactions: (I). Elucidation of the mechanism for histamine release inhibition. Immunopharmacol Immunotoxicol, 1992. 14(1-2): p. 191-205. [4]. Kohyama, T., et al., A novel antiallergic drug epinastine inhibits IL-8 release from human eosinophils. Biochem Biophys Res Commun, 1997. 230(1): p. 125-8.
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