2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Biological activity
Description
CAS NO.：107868-30-4 Product Name：Exemestane Synonyms：6-Methylene-androsta-1,4-diene-3,17-dione;6-methylenandrosta-1,4-diene-3,17-dione;6-METHYLENEANDROSTA-1,4-DIENE-3,17-DIONE;10,13-dimethyl-6-methylidene-7,8,9,10,11,12,13,14,15,16-decahydrocyclopenta[a]phenanthrene-;EXEMESTANE;FCE-24304;AROMASIN;EXEMESTANCE;ExeMestane(AroMasin);Anti-Estrogen AI Exemestaneknightlabs_leeisun;6-methylenandrost-1,4-diene-3,17-dione;androsta-1,4-diene-6-methylene-3,17-dione;CE24304;EXALAMIDE;EXE;Exemestan;ExemestaneF;FCE 24304;PNU155971;ExeMestine;Exemestane D2;ExeMestane (USP);Exemestanum;Exemestano;Exemestanum [INN-Latin];Exemestano [INN-Spanish];Exemestane [USAN:INN:BAN];FCE24304;Aromasine;NY22HMQ4BX EINEC:7463 Molecular Formula：C20H24O2 Molecular Weight：296.4034
Target:
Aromatase
In Vivo
In Vitro
Kinase Assay
Cell Assay
Animal Administration
References
[1]. Di Salle, E., et al., Novel aromatase and 5 alpha-reductase inhibitors. J Steroid Biochem Mol Biol, 1994. 49(4-6): p. 289-94.
[2]. Miki, Y., et al., Effects of aromatase inhibitors on human osteoblast and osteoblast-like cells: a possible androgenic bone protective effects induced by exemestane. Bone, 2007. 40(4): p. 876-87.
[3]. Wang, X. and S. Chen, Aromatase destabilizer: novel action of exemestane, a food and drug administration-approved aromatase inhibitor. Cancer Res, 2006. 66(21): p. 10281-6.
[4]. Goss, P.E., et al., Effects of the steroidal aromatase inhibitor exemestane and the nonsteroidal aromatase inhibitor letrozole on bone and lipid metabolism in ovariectomized rats. Clin Cancer Res, 2004. 10(17): p. 5717-23.
[5]. Zaccheo, T., D. Giudici, and E. Di Salle, Inhibitory effect of combined treatment with the aromatase inhibitor exemestane and tamoxifen on DMBA-induced mammary tumors in rats. J Steroid Biochem Mol Biol, 1993. 44(4-6): p. 677-80.
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