Ezatiostat(TER199; TLK199) Datasheet DC Chemicals
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Cat.No DC7204
Name Ezatiostat(TER199; TLK199)

Chemical Properties

CAS 168682-53-9
Formula C27H35N3O6S
MW 529.6483
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological activity

Description
Target:
In Vivo
In Vitro Ezatiostat causes dissociation of the enzyme from the jun-N-terminal kinase/c-Jun (JNK/JUN) complex, leading to JNK activation by phosphorylation. The therapeutic action of ezatiostat appears to include both proliferation of normal myeloid progenitors as well as apoptosis of the malignant clone[1].
Kinase Assay
Cell Assay
Animal Administration

References

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