F-1 Datasheet DC Chemicals
Description F-1 is a potent ALK and ROS1 dual inhibitor, suppresses phospho-ALK and its relative downstream signaling pathways, with IC50s of 2.1 nM, 2.3 nM, 1.3 nM and 3.9 nM for ALKWT, ROS1WT, ALKL1196M and ALKG1202R, respectively.
Cat.No DC60733
Name F-1

Chemical Properties

CAS 2244775-31-1
Formula C22H27CLN8O3S
MW 519.019581079483
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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