FG2216 Datasheet DC Chemicals
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Cat.No DC8195
Name FG2216

Chemical Properties

CAS 223387-75-5
Formula C12H9CLN2O4
MW 280.6639
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological activity

Description CAS NO.：223387-75-5
Product Name：N-[(1-Chloro-4-hydroxyisoquinolin-3-YL)carbonyl]glycine
Synonyms：Glycine, N-[(1-chloro-4-hydroxy-3-isoquinolinyl)carbonyl]-;FG 2216;FG-2216;YM-311;IOX 3;N-[(1-Chloro-4-hydroxy-3-isoquinolinyl)carbonyl]glycine;YM 311;[[(1-Chloro-4-hydroxyisoquinolin-3-yl)carbonyl]amino]acetic acid;FG 2216 (erythropoietic agent);FG2216;N-[(1-CHLORO-4-HYDROXYISOQUINOLIN-3-YL)CARBONYL]GLYCINE;RU921DS4Z5;2-(1-chloro-4-hydroxyisoquinoline-3-carboxamido)acetic acid;UN9;2-[(1-chloro-4-hydroxyisoquinoline-3-carbonyl)amino]acetic acid;Isoquinoline 3;4bqx;OUQVKRKGTAUJQA-UHFFFAOYSA-N;4ie6;2y34;BCP15220;AOB87331;(((1-Chloro-4-hyd
EINEC:
Molecular Formula：C12H9CLN2O4
Molecular Weight：280.6639
Target:
In Vivo
In Vitro
Kinase Assay
Cell Assay
Animal Administration

References

[1]. Hong YR, et al. [(4-Hydroxyl-benzo[4,5]thieno[3,2-c]pyridine-3-carbonyl)-amino]-acetic acid derivatives; HIF prolyl 4-hydroxylase inhibitors as oral erythropoietin secretagogues. Bioorg Med Chem Lett. 2013 Nov 1;23(21):5953-7. [2]. Hsieh MM, et al. HIF prolyl hydroxylase inhibition results in endogenous erythropoietin induction, erythrocytosis, and modest fetal hemoglobin expression in rhesus macaques. Blood. 2007 Sep 15;110(6):2140-7.
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