FK-888 Datasheet DC Chemicals

Description	FK-888 is a selective, high affinity tachykinin NK1 receptor antagonist (Ki = 0.69 nM) that displays 320-fold selectivity for human over rat NK1 receptors. FK-888 inhibits substance P-induced contraction of isolated guinea pig trachea (IC50 = 32 nM) and inhibits substance P-induced airway constriction in vivo.
Cat.No	DC33273
Name	FK-888

Chemical Properties

CAS	138449-07-7
Formula	C36H36N4O4
MW	588.69544
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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