FLT3-IN-1(SKLB4771) Datasheet DC Chemicals

Description	FLT3-IN-1(SKLB4771) is a novel potent and selective Flt3 inhibitor with IC50 of 10 nM; against FLT3-ITD-expressing MV4-11 cells with IC50 of 6 nM.
Cat.No	DC8230
Name	FLT3-IN-1(SKLB4771)

Chemical Properties

CAS	1370256-78-2
Formula	C25H27N7O3S2
MW	537.66
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

[1]. Li WW, et al. Discovery of the novel potent and selective FLT3 inhibitor 1-{5-[7-(3- morpholinopropoxy)quinazolin-4-ylthio]-[1,3,4]thiadiazol-2-yl}-3-p-tolylurea and its anti-acute myeloid leukemia (AML) activities in vitro and in vivo. J Med Chem. 2012 Apr 26;55(8):3852-66.

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