G6PD activator AG1 Datasheet DC Chemicals
Description G6PD activator AG1 (AG1) is a specific, small molecule that increases the activity of the wild-type, Canton mutant (R459L, EC50=3 uM) and several other common G6PD mutants; displays no effect on the dimerization or activity of several other NAD- or NADP+-dependent dimeric or tetrameric enzymes, including 6PGD, GAPDH, ALDH2, and ALDH3A1; attenuates ROS-induced pericardial edema in a G6PD-dependent manner in zebrafish, reduces hemolysis of human erythrocytes
Cat.No DC12438
Name G6PD activator AG1

Chemical Properties

CAS 421581-52-4
Formula C24H30N4S2
MW 438.652
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

[1]. https://patents.google.com/patent/WO2019023264A1/en?oq=WO2019023264A1
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