GNE-495 Datasheet DC Chemicals

Description	GNE-495 is a potent and Selective MAP4K4 Inhibitor with IC50 of 3.7 nM.
Cat.No	DC10546
Name	GNE-495

Chemical Properties

CAS	1449277-10-4
Formula	C22H20FN5O2
MW	405.4249
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

[1]. Ndubaku CO et al. Structure-Based Design of GNE-495, a Potent and Selective MAP4K4 Inhibitor with Efficacy in Retinal Angiogenesis. ACS Med Chem Lett. 2015 Jun 29;6(8):913-8.

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