GNE-6640 Datasheet DC Chemicals
Description GNE-6640 is a potent, selective USP7 inhibitor with IC50 of 0.75 uM; dislpalys selectivity over USP47 and USP5 (IC50>200 uM).
Cat.No DC12495
Name GNE-6640

Chemical Properties

CAS 2009273-67-8
Formula C20H18N4O
MW 330.3831
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

[1]. Kategaya L, et al. USP7 small-molecule inhibitors interfere with ubiquitin binding. Nature. 2017 Oct 26;550(7677):534-538.
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