GNF-1331 Datasheet DC Chemicals
Description GNF-1331 is a Potent, Selective, and Orally Bioavailable Porcupine Inhibitor (IC50 = 12 nM). Blockade of aberrant Wnt signaling is an attractive therapeutic approach in multiple cancers. Wnt signaling is tightly controlled during cellular proliferation, differentiation, and embryonic morphogenesis. Aberrant activation of this pathway plays a critical role in a variety of cancers, such as cutaneous squamous cell carcinoma (SCC), breast cancer, and colorectal cancer.
Cat.No DC32531
Name GNF-1331

Chemical Properties

CAS 603101-22-0
Formula C20H20N6O2S2
MW 440.54
Storage

References

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