GSK621 (GSK 621;GSK-621) Datasheet DC Chemicals

Description	GSK621 (GSK-621) is a potent, specific AMPK agonist (activator), induces cytotoxicity in AML (IC50=13-30 uM) but not in normal hematopoietic cells; GSK621 is more potent than A-769662 at inducing AMPK activation, as measured by the level of ACC phosphoryl
Cat.No	DC29234
Name	GSK621 (GSK 621;GSK-621)

Chemical Properties

CAS	1346607-05-3
Formula	C26H20CLN3O5
MW	489.91
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

[1]. Pierre Sujobert, et al. Co-activation of AMPK and mTORC1 Induces Cytotoxicity in Acute Myeloid Leukemia. Cell Rep. 2015 Jun 9;11(9):1446-57.

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