GW 583340 dihydrochloride Datasheet DC Chemicals
Description GW 583340 dihydrochloride is a potent dual EGFR/ErbB2 tyrosine kinase inhibitor (IC50 values are 0.01 and 0.014 μM respectively). GW 583340 dihydrochloride selectively inhibits growth of human tumor cells overexpressing EGFR and ErbB2 (IC50 values are 0.11 μM for inhibition of HN5, N87 and BT474 tumor cell lines vs. > 30 μM for inhibition of non-tumor cell line HFF).
Cat.No DC33279
Name GW 583340 dihydrochloride

Chemical Properties

CAS 1173023-85-2
Formula C28H27CL3FN5O3S2
MW 671.02
Storage

References

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