Gemcitabine monophosphate disodium salt monohydrate Datasheet DC Chemicals
Description Gemcitabine monophosphate disodium salt, also called GemMP, is a monophosphate derivative of Gemcitabine. Gemcitabine (Gem) is a deoxycytidine analog that is effective against pancreatic cancer and other malignancies following conversion to the 5'-O-mono-, di- and tri-phosphate forms. GemMP decreased tumor cell growth at concentrations ranging from 1 to 50 nM. GemMP is a potent cytotoxic agent that serves to induce apoptosis in association with increased Fas expression in cultured thyroid cancer cell lines. (Anticancer Res. 2000 Sep-Oct;20(5A):2915-22).
Cat.No DC32499
Name Gemcitabine monophosphate disodium salt monohydrate

Chemical Properties

CAS 116371-67-6
Formula C9H12F2N3NA2O8P
MW 405.15811
Storage

References

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