Golvatinib (E7050) Datasheet DC Chemicals

Description	E-7050 is hepatocyte growth factor receptors (HGFR).
Cat.No	DC5065
Name	Golvatinib (E7050)

Chemical Properties

CAS	928037-13-2
Formula	C33H37F2N7O4
MW	633.688194036484
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

[1]. Nakagawa T et al. E7050: a dual c-Met and VEGFR-2 tyrosine kinase inhibitor promotes tumor regression and prolongs survival in mouse xenograft models. Cancer Sci, 2010, 101(1), 210-215. [2]. Wang W et al. Met kinase inhibitor E7050 reverses three different mechanisms of hepatocyte growth factor-induced tyrosine kinase inhibitor resistance in EGFR mutant lung cancer. Clin Cancer Res, 2012, 18(6), 1663-1671.

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