HKI272 maleate Datasheet DC Chemicals
Description Neratinib, also known as HKI-272 or PB272, is an orally available, irreversible inhibitor of the HER-2 receptor tyrosine kinase with potential antineoplastic activity. Neratinib binds to the HER-2 receptor irreversibly, thereby reducing autophosphorylation in cells, apparently by targeting a cysteine residue in the ATP-binding pocket of the receptor.
Cat.No DC38096
Name HKI272 maleate

Chemical Properties

CAS
Formula C34H33CLN6O7
MW 673.123
Storage

References

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