ISOQUERCITRIN Datasheet DC Chemicals
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Cat.No DC23107
Name ISOQUERCITRIN

Chemical Properties

CAS 482-35-9
Formula C21H20O12
MW 464.3763
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological activity

Description CAS NO.：482-35-9
Product Name：Isoquercitrin
Synonyms：4H-1-Benzopyran-4-one,2-(3,4-dihydroxyphenyl)-3-(b-D-glucopyranosyloxy)-5,7-dihydroxy-;Quercetin 3-β-D-glucoside;3,3′,4′,5,7-Pentahydroxyflavone 3-β-glucoside, Isoquercitrin, Quercetin 3-β-D-glucoside;ISOQUERCETIN(P);ISOQUERCETIN(P) (AHP Verified)(REQUEST QUOTE) PrintBack;ISOQUERCETIN(RG);Isoquercitrin;Quercetin 3-glucoside;Quercetin 3-O-β-D Glucoside;Quercetin-3-O-glucopyranoside;2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one;Isoquercetrin;NSC 115918;Q 5;Quercetin 3-D-glucoside;Quercetin 3-O-glucopyranoside;Quercetin 3-O-glucoside;Quercetin 3-O-beta-D-glucopyranoside;Quercetin 3-O-beta-D-glucoside;Quercetin 3-O-beta-D-glycoside;Quercetin 3-O-beta-glucoside;2-(3,4-Dihydroxyphenyl)-3-(beta-D-glucopyranosyloxy)-5,7-dihydroxy-4H-1-benzopyran-4-one;[ "Quercetin 3-O-glucoside", " Hirsutrin" ];Isoquercetin;Hirsutrin;3-Glucosylquercetin;Glucosyl 3-quercetin;Quercetol 3-glucoside;Quercetol 3-monoglucoside;Quercetin 3-monoglucoside;Isotrifoliin;Quercetin 3-beta-glucoside;quercetin-3-glucoside;Quercetin 3-beta-O-glucoside;quercetin-3-O-glucoside;3-beta-D-Glucosylquercetin;6HN2PC637T;CHEB
EINEC:115918
Molecular Formula：C21H20O12
Molecular Weight：464.3763
Target:
In Vivo
In Vitro Quercetin-3-glucoside (5-20 μM; 24 hours) substantially reduces ethanol-induced cytotoxicity , protects hepatic cells against ethanol‐stimulated liver injury[1].Quercetin-3-glucoside (10 μM; pre-treat 1 hour) dramatically downregulates the levels of ethanol-induced iNOS protein expression in HepG2 cells[1]. Cell Viability Assay[1] Cell Line: HepG2 cells Concentration: 5 μM, 10 μM, 20 μM Incubation Time: 24 hours Result: Caused significantly enhanced cell viability as positive controls. Western Blot Analysis[1] Cell Line: HepG2 cells Concentration: 10 μM Incubation Time: 1 hour Result: Decreased ethanol‐ induced iNOS protein expression.
Kinase Assay
Cell Assay
Animal Administration

References

[1]. Lee S, et al. Relative protective activities of quercetin, quercetin-3-glucoside, and rutin in alcohol-induced liver injury. J Food Biochem. 2019 Aug 5:e13002. [2]. Tan C, et al. Modulation of nuclear factor-κB signaling and reduction of neural tube defects by quercetin-3-glucoside in embryos of diabetic mice. Am J Obstet Gynecol. 2018 Aug;219(2):197.e1-197.e8.
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