Idasanutlin (RG-7388) Datasheet DC Chemicals

Description	RG7388 is an oral, selective, small molecule MDM2 antagonist that inhibits binding of MDM2 to p53.
Cat.No	DC7821
Name	Idasanutlin (RG-7388)

Chemical Properties

CAS	1229705-06-9
Formula	C31H29CL2F2N3O4
MW	616.48
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

[1]. Ding Q, et al. Discovery of RG7388, a potent and selective p53-MDM2 inhibitor in clinical development. J Med Chem. 2013 Jul 25;56(14):5979-83. [2]. Higgins B, et al. Preclinical optimization of MDM2 antagonist scheduling for cancer treatment by using a model-based approach. Clin Cancer Res. 2014, 20(14), 3742-3752.

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