Isoniazid(Tubizid) Datasheet DC Chemicals
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Cat.No DCAPI1242
Name Isoniazid(Tubizid)

Chemical Properties

CAS 54-85-3
Formula C6H7N3O
MW 137.14
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological activity

Description CAS NO.:54-85-3
Product Name:
Synonyms:Tubizid, Laniazid, Nydrazid, Isonicotinylhydrazine
EINEC:200-214-6
Molecular Formula:C6H7N3O
Molecular Weight:137.14
Target:
In Vivo
In Vitro
Kinase Assay
Cell Assay
Animal Administration

References

[1]. Suarez, J., et al., An oxyferrous heme/protein-based radical intermediate is catalytically competent in the catalase reaction of Mycobacterium tuberculosis catalase-peroxidase (KatG). J Biol Chem, 2009. 284(11): p. 7017-29. [2]. Timmins, G.S., et al., Nitric oxide generated from isoniazid activation by KatG: source of nitric oxide and activity against Mycobacterium tuberculosis. Antimicrob Agents Chemother, 2004. 48(8): p. 3006-9. [3]. Singh, R., et al., PA-824 kills nonreplicating Mycobacterium tuberculosis by intracellular NO release. Science, 2008. 322(5906): p. 1392-5. [4]. Ahmad, Z., et al., Biphasic kill curve of isoniazid reveals the presence of drug-tolerant, not drug-resistant, Mycobacterium tuberculosis in the guinea pig. J Infect Dis, 2009. 200(7): p. 1136-43.
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