KRAS inhibitor-9 Datasheet DC Chemicals

Description	KRAS inhibitor-9, a potent KRAS inhibitor (Kd=92 μM), blocks the formation of GTP-KRAS and downstream activation of KRAS. KRAS inhibitor-9 binds to KRAS G12D, KRAS G12C and KRAS Q61H protein with a moderate binding affinity. KRAS inhibitor-9 causes G2/M cell cycle arrest and induces apoptosis. KRAS inhibitor-9 selectively inhibits the proliferation of NSCLC cells with KRAS mutation but not normal lung cells.
Cat.No	DC41041
Name	KRAS inhibitor-9

Chemical Properties

CAS	300809-71-6
Formula	C13H9CLN2S2
MW	292.806958913803
Storage	Powder-20°C3 years 4°C2 yearsIn solvent-80°C6 months-20°C1 month

References

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