L778123 dihydrochloride Datasheet DC Chemicals
Description L-778123 is an inhibitor of FPTase and GGPTase-I, which was developed in part because it can completely inhibit Ki-Ras prenylation. The combination of L-778,123 and radiotherapy at dose level 1 showed acceptable toxicity in patients with locally advanced pancreatic cancer. Radiosensitization of a patient-derived pancreatic cancer cell line was observed.
Cat.No DC32737
Name L778123 dihydrochloride

Chemical Properties

CAS 183499-56-1
Formula C22H22CL3N5O
MW 478.802
Storage

References

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