L-189 Datasheet DC Chemicals

Description	L-189 is a DNA ligase I, III and IV inhibitor (IC50 values are 5, 9 and 5 μM respectively) that blocks DNA binding (Ki = 5 μM for DNA ligase I).
Cat.No	DC8136
Name	L-189

Chemical Properties

CAS	64232-83-3
Formula	C11H10N4OS
MW	246.2883
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

[1]. Xi Chen, Shijun Zhong, Xiao Zhu, et al. Rational Design of Human DNA Ligase Inhibitors that Target Cellular DNA Replication and Repair. Cancer Res 2008; 68: (9). May 1, 2008

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