Letrozole Datasheet DC Chemicals
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Cat.No DCAPI1414
Name Letrozole

Chemical Properties

CAS 112809-51-5
Formula C17H11N5
MW 285.3027
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological activity

Description CAS NO.：112809-51-5
Product Name：Letrozole
Synonyms：4,4'-((1H-1,2,4-Triazol-1-yl)methylene)dibenzonitrile;4,4'-(1H-1,2,4-TRIAZOL-1-YLMETHYLENE) BIS-BENZONITRILE;CGS-20267;FEMARA;LETROZOL;LetrozoleUsp28;CGS-20267, Femara;LETRAZOLE;letrozolex;Lelrozol;1-[BIS(4-CYANOPHENYL)METHYL]-1,2,4-TRIAZOLE;4,4'-(1H-1,2,4-Triazol-1-ylmethylene)dibenzonitrile;4,4'-(1H-1,2,4-Triazole-1-ylmethylene)bisbenzonitrile;4,4'-[(1H-1,2,4-Triazole-1-yl)methylene]dibenzonitrile;Letrozole;4,4'-((1H-1,2,4-Triazol-1-yl)-methylene)dibenzonitrile;4,4'-(1H-1,2,4-Triazol-1-ylmethylene)bisbenzonitrile;4-[(4-cyanophenyl)-(1,2,4-triazol-1-yl)methyl]benzonitrile;Letrozole (Femara);[14C]-Letrozole;4,4'-(1H-1,2,4-triazol-1-ylmethylene)bis(benzonitrile);CGS20267;Femera;Letoval;UNII-7LKK855W8I;4,4′-(1H-1,2,4-Triazol-1-ylmethylene)bisbenzonitrile;Letroz;Lerozole;Letrozole99%;Letrozole Impurity;CGS 20267;4,4'-(1H-1,2,4-triazol-1-ylmethanediyl)dibenzonitrile;Benzonitrile, 4,4'-(1H-1,2,4-triazol-1-ylmethylene)bis-;C17H11N5;4-[(4-CYANOPHENYL)(1H-1,2,4-TRIAZOL-1-YL)METHYL]BENZONITRILE;7LKK855W8I;4,4'-(1h-1,2,4-triazol-1-yl;4,4'-(1h-1,2,4-triazol-1-ylmethylene)bisben
EINEC:7461
Molecular Formula：C17H11N5
Molecular Weight：285.3027
Target:
In Vivo
In Vitro
Kinase Assay
Cell Assay
Animal Administration

References

[1]. Haynes, B.P., et al., The pharmacology of letrozole. J Steroid Biochem Mol Biol, 2003. 87(1): p. 35-45. [2]. Bhatnagar, A.S., et al., Highly selective inhibition of estrogen biosynthesis by CGS 20267, a new non-steroidal aromatase inhibitor. J Steroid Biochem Mol Biol, 1990. 37(6): p. 1021-7. [3]. Dellapasqua, S. and M. Colleoni, Letrozole. Expert Opin Drug Metab Toxicol, 2010. 6(2): p. 251-9. [4]. Lee, K., et al., An in vivo model of intratumoural aromatase using aromatase-transfected MCF7 human breast cancer cells. Int J Cancer, 1995. 62(3): p. 297-302.
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