Lipoic acid Datasheet DC Chemicals
Description Lipoic acid is a selective, small molecule large-conductance Ca(2+)-activated K(+) channel (BKCa, KCa1.1, MaxiK) positive modulator with EC50 of 11 uM. Lipoic acid shows a favorable selectivity profile on Nav, Cav, SK, and IK channels. Lipoic acid causes distinct activation from a concentration of 0.3 and 10 µM Lipoic acid left-shifted the voltage activation curve by 60 mV. Lipoic acid reduces spontaneous phasic contractions in guinea pig urinary bladder strips at 1 uM, while having only a modest effect on contractions evoked by electrical field stimulation (EFS) and no effect on high K+-induced contractions.
Cat.No DCL-027
Name Lipoic acid

Chemical Properties

CAS 62-46-4
Formula C8H14O2S2
MW 206.3256
Storage 4°C for 1 year, -20°C for more than 2 years

References

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