Lusutrombopag（S-888711） Datasheet DC Chemicals
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Cat.No DC9938
Name Lusutrombopag（S-888711）

Chemical Properties

CAS 1110766-97-6
Formula C29H32CL2N2O5S
MW 591.5458
Storage 4°C for 1 year, -20°C for more than 2 years

Biological activity

Description CAS NO.：1110766-97-6
Product Name：Lusutrombopag
Synonyms：Lusutrombopag;S-888711;(2E)-3-[2,6-Dichloro-4-[[[4-[3-[(1S)-1-(hexyloxy)ethyl]-2-methoxyphenyl]-2-thiazolyl]amino]carbonyl]phenyl]-2-methyl-2-propenoic acid;S 888711;mulpleta;6LL5JFU42F;(S,E)-3-(2,6-Dichloro-4-((4-(3-(1-(hexyloxy)ethyl)-2-methoxyphenyl)thiazol-2-yl)carbamoyl)phenyl)-2-methylacrylic acid;2-Propenoic acid, 3-[2,6-dichloro-4-[[[4-[3-[(1S)-1-(hexyloxy)ethyl]-2-methoxyphenyl]-2-thiazolyl]amino]carbonyl]phenyl]-2-methyl-, (2E)-;Lusutrombopag [USAN:INN];Mulpleta (TN);2-Propenoic acid, 3-(2,6-dichloro-4-(((4-(3-((1S)-1-(hexyloxy)ethyl)-2-methoxyphenyl)-2-thiazolyl)amino)carbonyl)phenyl)-2-methyl-,
EINEC:
Molecular Formula：C29H32CL2N2O5S
Molecular Weight：591.5458
Target:
In Vivo
In Vitro Lusutrombopag acts selectively on the human TPO receptor and activates signal transduction pathways that promote the proliferation and differentiation of bone marrow cells into megakaryocytes, thereby increasing platelet levels[1].
Kinase Assay
Cell Assay
Animal Administration

References

[1]. Kim ES, et al. Lusutrombopag: First Global Approval. Drugs. 2016 Jan;76(1):155-8.
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