MI-3454 Datasheet DC Chemicals

Description	MI-3454 is an orally active, highly potent and selective menin-MLL1 interaction inhibitor with an IC50 of 0.51 nM. MI-3454 inhibits proliferation, induces differentiation and complete remission or regression of leukemia in mouse models of MLL1-rearranged or NPM1-mutated leukemia through downregulation of key genes involved in leukemogenesis.
Cat.No	DC40900
Name	MI-3454

Chemical Properties

CAS	2134169-43-8
Formula	C32H35F3N8OS
MW	636.73
Storage	4°C, stored under nitrogen*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

References

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