MI-538 Datasheet DC Chemicals

Description	MI-538 is an inhibitor of the interaction between menin and MLL fusion proteins with an IC50 of 21 nM.
Cat.No	DC10287
Name	MI-538

Chemical Properties

CAS	1857417-10-7
Formula	C27H25F3N8OS
MW	566.60
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

[1]. Borkin D, et al. Property Focused Structure-Based Optimization of Small Molecule Inhibitors of the Protein-Protein Interaction between Menin and Mixed Lineage Leukemia (MLL). J Med Chem. 2016 Feb 11;59(3):892-913.

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