MK-8153 Datasheet DC Chemicals

Description	MK-8153 is a potent and selective ROMK (potassium channel, Kir1.1) blocker with IC50 of 2.5 nM in rat ROMK, rKir1.1/HEK293 cells. MK-8153 has a longer projected human half-life (~14 h) than MK-7145, which should provide a reduced peak-to-trough exposure ratio and potentially, a smoother, more extended diuretic response.
Cat.No	DC55020
Name	MK-8153

Chemical Properties

CAS	1548286-45-8
Formula	C24H28N2O6
MW	440.49
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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