ML334 Datasheet DC Chemicals
Description ML334 is a potent, cell permeable activator of NRF2 by inhibition of Keap1-NRF2 protein-protein interaction. ML334 binds to Keap1 Kelch domain with a Kd of 1 μM. ML334 stimulates NRF2 expression and nuclear translocation and induces antioxidant response elements (ARE) activity.
Cat.No DC28273
Name ML334

Chemical Properties

CAS 1432500-66-7
Formula C26H26N2O5
MW 446.5
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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