Mal-PEG4-Val-Cit-PAB-PNP Datasheet DC Chemicals
Description Mal-PEG4-Val-Cit-PAB-PNP is a linker for Antibody-Drug-Conjugation (ADC). The Val-Cit will specifically be cleaved by catepsin B. Because this enzyme is only present in the lysosome, the ADC payload will only be released in the cell. The Azido group will react with DBCO, BCN or other Alkyne groups through click chemistry. The hydrophilic PEG spacer increases solubility in aqueous media.
Cat.No DC35876
Name Mal-PEG4-Val-Cit-PAB-PNP

Chemical Properties

CAS
Formula C40H53N7O15
MW 871.9
Storage

References

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