Marein Datasheet DC Chemicals
Description Marein has the neuroprotective effect due to a reduction of damage to mitochondria function and activation of the AMPK signal pathway. Marein improves insulin resistance induced by high glucose in HepG2 cells through CaMKK/AMPK/GLUT1 to promote glucose uptake, through IRS/Akt/GSK-3β to increase glycogen synthesis, and through Akt/FoxO1 to decrease gluconeogenesis. Marein is a HDAC inhibitor with an IC50 of 100 μM. Marein has beneficial antioxidative, antihypertensive, antihyperlipidemic and antidiabetic effects.
Cat.No DC41462
Name Marein

Chemical Properties

CAS 535-96-6
Formula C21H22O11
MW 450.39
Storage 4°C, protect from light*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

References

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